CHEMISTRY OF HOMEOPATHY and the FDA

LIGHTNING IN A BOTTLE 

Avogadro’s Constant hypothesis predicts electron pressure and the asymptote at infinite dilution.

Avogadro’s limit doesn’t apply to absence of solute in homeopathic remedies because of electron pressure enthalpy, a measure of energy in a thermodynamic system. its native heat, from the Schumann resonances, the background geomagnetic field, discovered first by Tesla, later by Schumann mid-twentieth century. Ionization of the solvent by dissociation of the solute molecule has been confirmed in the ultra-dilute remedy.

The solute in a dilute homeopathic remedy is not molecular because of de-ionization into electrons, . There are measures within analytic chemistry which prove it, such as conductance tests and transmission electron microscopy  (TEM).

All of the extreme controversy over whether or not the homeopathic remedy is placebo or verum, whether or not these materials are medically effective, and all of these phony money offers to “prove homeopathy”, conveniently avoid this simple, demonstrable fact, a fact that separates homeopathy from fiction: the solute in highly diluted solutions used as homeopathic drugs is ionized and can be physically detected by conventional chemical analysis.

Students and professors of electrochemistry should be well aware of this elementary principle of molecular dissociation, that as the solute presumably decreases, thins out and changes phase fron condensed to plasma, its conductivity increases to an asymptote and evidence of the solute persists in the solvent despite an apparent infinite number of dilutions.

Why or how the solute persists in infinite dilution is not clear, but strange as it may seem to the zenophobic, it does so, no matter how dilute it is in serial dilutions.

According to Copeland, the solute is not completely deionized until the sixth decimal dilution, at which point the aqueous solvent has completely dissociated the molecular structure of the solute by means of hydrolysis.

There are tests of molar conductance that demonstrate this.

The Chemistry of Homeopathy under the Food and Drug Administration (FDA)

FDA NOTICE FOR HOMEOPATHY
On April 20-21, 2015, the Food and Drug Administration (FDA) held a public hearing at its White Oak Campus to obtain information and comments from stakeholders about the current use of human drug and biological products labeled as homeopathic, as well as the Agency’s regulatory framework for such products. These products include prescription drugs and biological products labeled as homeopathic and over-the-counter (OTC) drugs labeled as homeopathic. FDA is still seeking written comments from all interested parties, including, but not limited to, consumers, patients, caregivers, health care professionals, patient groups, and industry. FDA is seeking input on a number of specific questions, but is interested in any other pertinent information participants would like to share. Please refer to the following documents for more information:
Federal Register Notice
Submit Comments to the Public Docket

http://www.fda.gov/Drugs/NewsEvents/ucm430539.htm

PROCEEDINGS STOPPED FOR A VOLTE FACE ANNOUNCEMENT: THE CHEMISTRY OF HOMEOPATHY HAS BEEN DISCOVERED!

As dry as this may seem at first, this is really a fascinating topic, and very psimon3 2010_05_01_16_12_21 001wet. A few months ago The Washington Post reported that by analyzing edit changes made by citizen contributors of articles in the online encyclopedia Wikipedia, they were able to determine that the two most contentious topics in the Western world are Jesus Christ and homeopathy.

HOMEOPATHY?

Now you might not be surprised to hear that Jesus is still stirring up trouble, but without further erudition . . unless you’ve been in or close to the pot being stirred . . you might be a bit perplexed when told something as innocuous as “homeopathy” is rivaling Christ for the bad boy of the Western world distinction; but I would venture to say that if you  go further East I reckon homeopathy is also kicking Muhammed and Buddha in the skirts for the same title; and get this, it should be even even more perplexing to hear that both doctrines of Christ and homeopathy share atheists as their primary detractors!

“What’s this you say?”

Yes, it pains me to say it, but it’s true. Both Jesus and homeopathy are healers and both kickoveer money tables. The mere mention of the word “homeopathy” can send a malinformed atheist into a fit of glossolalia and make him dance like St. Vitus. There are innumerable high profile atheists, like Richard Dawkins and James Randi, who, when they’re not ridiculing a belief in the Deity and knocking the noses off of marbled saints, are tearing up the well manicured lawn in front of the great doctrine of Hahnemann House, crying a liturgy of shameless pseudoscience, so much so that homeopathy is something of a pariah in the Western mainstream media so slavishly chained to academic science and big money patent medicine . .  which in the case of homeopathy is now itself mouthing pseudoscience!

Now just to make this volte face clear, I’m not accusing homeopathy of being pseudoscience, no! I’m accusing skepticism of it! I’m here in this article doing something that’s never been done before in modern times, and certainly never done to this extent ever heretofore: I’m making the first installment of a presentation where I introduce the chemical principle of what has been thought to be a scientific impossibility, and that my friends is the chemistry of what most material scientists have insisted was a placebo, hoax and fraud, where every man jack of them is a patholgical atheist!

It’s true! And please don’t get me wrong or take me as poe. At times I have found a grudging respect for atheists. I am even inclined to believe they are amongst God’s favorites; they may not be speaking to him, but at least they’re not speaking for him as so many believers do.  But they don’t show this grace for homeopathy, nor in reality do they show it for science, and yes I know, I know, I’ve just thrown more boiling water on the storm troopers by saying that.

I am noting this to reveal an exposition of a pathology that stands in the way of accepting a known chemical principle. Be it because of pride or lacking a gear for reverse travel, they say and will continue to say, as they have said before, incorrectly, that there is no known chemistry to explain the action of the highly aqueous diluted materials used as medicine in the practice of homeopathy . .

WRONG!

. . and so they will still say,  even though it can now be explained to them with a chemical principal to the contrary, that because there’s not one MOLECULE in it of anything but plain water, the homeopathic solution cannot have any specific medical action of its own; therefore homeopathy is without reason and there can be no acceptable evidence for it; all evidence then for the fraud is dismissed!

That is what they say, the rampaging patent medicine engine cheers them on, and they are wrong. There is a widely known chemical principle that supports homeopathy and there are now widely known properties within classical chemistry that prove the action of these drugs. That neither homeopath nor skeptic is aware of the classical chemistry of homeopathy suggests that, as a gesture of compromise with other more insidious reasons, that, lacking finite limitations, the basic underlying chemical principle is sensed by the human mind and rejected . . and this is a premier example of a scientific cognitive dissonance. Both principle and property have been gathering dust in science, and the link between homeopathy and chemistry, once known, has up until now apparently been forgotten, ignored or expelled from classical science for over 100 years. Like a brazen Frankenstein I stand before the torchlit mob and shout “It lives!”

In other words, there is a classical chemistry to explain the potency of what former scientists have been screaming are inert placebos, incapable of intrinsically delivering the effects of their label. Furthermore, and in terms of the FDA, this next piece of information ought to bring everyone still sitting to their feet and the hearing to a halt: The chemistry of homeopathy was first presented by the progenitor of the modern FDA, the chief sponsor of the Food Drug and Cosmetics Act (FDCA)!

INFINITE DILUTION

It should come as a great surprise . . if not shock and disbelief . . to proponent and opponent alike to learn — contrary to common belief and what is taught by putative skeptics, and medical and “homeopathy” schools alike — there is recognition within standard, classical chemistry, that with materials ionized by molecular dissociation in aqueous solutions, the properties of the solute are fixed and remain constantly in “infinite dilution”!

Furthermore, to the even greater distress of homeopath and skeptic alike, at least those who want to continue the obfuscation of supramolecular chemistry [the study of electric properties beyond the molecule] with homeopathy, associating the “homeopathic remedy” with the chemistry of molecular dissociation was done 106 years ago by none other than the medical doctor and professor of academic medicine who became a US Senator and the chief sponsor of FDA denture, the Food, Drug and Cosmetic Act (FDCA), the man who gave the FDA its teeth, Senator Royal S. Copeland A.M., M.D.

copeland2

Senator Royal S. Copeland, A.M., M.D.

In a 1909 article entitled “The Scientific Reasonableness of Homeopathy” by Royal S. Copeland, A.M., M.D.  he states:

“. . a chemical, technically an electrolyte, when dissolved, is dissociated into parts or particles smaller than the atoms and known as ions. The more dilute the solution the greater is the dissociation and consequently the atoms are less in number and the ions increased. In a solution infinitely dilute, the dissociation is absolute and the chemical is present only in a state of ionization.”

Read the whole article.   http://www.homeowatch.org/history/copeland.html

Although Copeland goes on to persuade using testimony from Kelvin and other authorities (while most homeopaths will remain paralyzed and silent) Copeland’s article will be dismissed in horror by skeptics, who will use its age and the fact that the author was a homeopath, as excuses for further obloquy of “homeopathy.”
There does indeed seem to be some confusion as to what exactly constitutes an ion, a confusion that persists to this day; but despite cries wishing for the contrary, modern classical chemistry still supports Copeland’s thesis, that the properties of ionized solutes remain constant throughout “infinite dilution.”
Running a search on Google for the number of appearances of “infinite dilution” returns an unbelievable 229,000 hits (search made on June 7th, 2015), and among these, numerous articles that support the principle of an asymptote solute in infinite dilution. Asymptote means approaching but never reaching zero, i.e., due to particle splitting of a solute in aqueous suspension, the concentration of solute ions will approach but never reach zero, no matter how many dilutions are made!

SCIENCE AS AMNESIAC
How is it then that skeptical opinion by professional organizations, engaging the media against homeopathy, can deny what is an orthodox explanation of FDA labeled “homeopathic” pharmaceuticals by modern classical claassical chemistry? They will volley to the end that a belief in homeopathy is delusional, when in fact the scientific principal of the properties of solutes remaining in infinite dilution is a well established fact, to be found online in the literature.

“It may sound like something out of a science fiction movie, but infinite dilution is a concept found in chemistry that is applied to the study of solvents — liquids — and solutes, the substances that are dissolved in solvents. This principle is used to test the properties of solutions and extrapolate or estimate their chemical reactions in varying environments.”
Read more : http://www.ehow.com/about_5459313_definition-infinite-dilution.html

What is infinite dilution – Answers.com
“Infinite dilution means such a large dilution so that when you add more solvent there is no change in concentration.”
http://www.answers.com › Wiki Answers › Categories › Science › Chemistry

“An infinitely dilute solution is one where there is a sufficiently large excess of water that adding any more does not cause any further heat to be absorbed or evolved. … The hydration enthalpy is the enthalpy change when 1 mole of gaseous ions dissolve in sufficient water to give an infinitely dilute solution. Hydration enthalpies are always negative.”
http://www.chemguide.co.uk/physical/energetics/solution.html
http://chemwiki.ucdavis.edu/Physical_Chemistry/Thermodynamics/State_Functions/Enthalpy/Enthalpy_Change_of_Solution

Wikipedia
“The law is based on the fact that only a portion of the electrolyte is dissociated into ions at ordinary dilution and completely at infinite dilution.”  en.wikipedia.org/wiki/Law_of_dilution

PDF: Theory of infinite dilution chemical potential

University of Illinois at Chicago

Fluid Phase Equilibria, 85 (1993) 141-151. Elsevier Science Publishers B.V., Amsterdam. 141. Theory of infinite dilution chemical potential. http://www.uic.edu/labs/trl/HamadInfiniteDilution.pdf 

A search in PUBMED for articles containing “infinite dilution” brought up a dizzying 620 abstracts.

http://www.ncbi.nlm.nih.gov/pubmed/?term=%22infinite+dilution%22

JERRY BLOWS UP TOM

This one mere fact, expressed as two words: INFINITE DILUTION, exposes this whole cat and mouse game of gotcha antagonism against the practice of homeopathy to be nothing more than ignorant pseudoscience. This is a monumental discovery. Anybody can look it up online and see it for themselves in a plethora of articles on the subject.
If infinite dilution is not a chemical fact that refers to the properties of the solute remaining in the solvent after unlimited serial dilutions, then perhaps one of these self-appointed celebrity spokesmen for science, such as Richard Dawkins, Penn Jillette or James “the Amazing” Randi et al; or caviling professors such as PZ Myers, Edzard Ernst, Joe Schwarc, David Colquhoun or Steven Novella et al can explain to us, in their own pseudoscientific terms, just what it really means.

MYSTERY OF WHY

Why have homeopathic physicians and manufacturers of homeopathic medicine not seized upon this acknowledged principle as an answer to critics who insist homeopathic medicines contain “nothing in them but plain water”? Why isn’t the burgeoning homeopathy industry insisting that homeopathic remedies be redesignated ionized pharmaceuticals?

The mystery of why standard chemistry’s concept of infinite dilution is not applied to the dilution dilemma of homeopathic medicine might at first seem as perplexing as infinite dilution itself. But dwell on it here a little longer and deeper truths emerge.

STUCK ON AVOGADRO

Due to the momentum gained by an incorrect interpretation of “Avogadros limit,” it will continue to be stated by skeptics, posing as rationalists, that by a process of reduction by dilution, the number of molecules of a solute will be reduced past the asymptote to zero by the 23rd decimal dilution, and this is presented as proof that homeopathic remedies contain none of the ingredient stated on a product labeled “homeopathic” and are therefore fraudulent. But there’s a reason why I italicize the word molecule in the context of Avogadro because this is where skeptic theory for homeopathic remedies having nothing of their labeled materials in them literally falls apart.

First, let’s examine what Avogadros constant, limit or number. Avogadro’s hypothesis as proof of an empty bottle . . is easily rebutted. Avogadro’s number is a constant, the ratio of solute particles to the solvent. It must be for particles, such as ions, not just molecules, in a volume of gas, not water. It doesn’t factor the perpetual production of ions by dissociation.

If a constant such as Avogadro’s, Faraday’s or Henry’s were applied to infinite dilution, it might state that due to repeated expansion and contraction of the ion’s domain within the aqueous host (by enthalpy) and contraction due to dissociation, the number of total ions in solution from the time of complete ionization will remain constant within a sinusoidal range throughout all subsequent dilutions.

The FDA then should address this argument and concern by stating that products registered as “homeopathic remedies” are in reality ionized pharmaceuticals, that they are supramolecular (beyond molecular) and their active constitutuion ionic, not molecular.

Now, this assertion of ionized pharmaceutical calls for a question of assay. How are the properties of the ionized solute detected in what are currently called homeopathic drugs, or remedies? Are there tests, trials or experiments that show the presence of an ionized solute in infinite dilution?

Copeland: “. . the laboratory has proven that the properties of a completely dissociated solution are the sum of all the ions present in the solution. This holds for such properties as conductivity, lowering of the freezing point, refraction equivalent, heat of neutralization, and undoubtedly, for any therapeutic effect possessed by the drug.”

Here then Copeland gives us four physical, non-clinical tests, or assays, from 1909, for ionized pharmaceuticals, tests that promise to separate and identify verum from placebo aliquots of the inert aqueous vehicle:

  1. Conductivity
  2. Freezing point
  3. Refraction equivalent
  4. Heat of neutralization

. . and modern chemistry has given us more; transmission electron microscopy (TEM) gives us a fifth assay that detects the actual presence of ions of the starting materials. http://homeoint.ru/pdfs/Extreme%20homeopathic%20dilutions%20retain%20starting%20%20materials-A%20nanoparticulate%20perspective.pdf

If not yet convinced, any real scientist will put aside his drumroll of ignorance or preconceived notions of what the homepathic remedy is when made aware of the National Institute for Standards and Technology (NIST) test protocol for infinite dilutions:

“Test 4: Infinite Dilution Test. This is a test for consistency in the limiting behavior of GE/(x1x2/RT) and the activity coefficients γ1 and γ2. The percent deviations in both limits are calculated: http://trc.nist.gov/TDE/Help/TDE103b/VLE-DataSets-ConsistencyTests/InfiniteDilution.htm

In lieu of this newly rediscovered chemistry for the materials used in homeopathy, the FDA should drop the term “homeopathic” and replace it with ionized or ionic as the description for these drugs.

I don’t know how it is that they can fight their way out of this paper bag. They and their secret police now stand accused of pseudoscience, the very thing they accused homeopathy of, and as funny as it is, I don’t know now how it is that they and “skepticism” can be taken seriously anymore.

John Henry Clarke, M.D.

The clinical proof has long been extant. If you really look at the semiological registers, most particularly the FDA recommended literature on the subject, (Dictionary of the Materia Medica by John Henry Clarke, M.D. http://www.homeoint.org/clarke/) you will find alternative answers to problems now being addressed almost solely by over-monetized patent medicine, and we all know, or should know, what a disaster it has been.

Death by Medicine http://www.webdc.com/pdfs/deathbymedicine.pdf
https://www.worstpills.org/

Although I am quite aware of the denials that will follow, with the chemistry of infinite dilution now well established in numerous explanations online, it is time to bring this existing, second, more humane pharmacopoeia of inexpensive, time tested, well documented, FDA sanctioned, effective medical materials out of the shadows into the real world of real medicine. This begins with the FDA recognizing what these materials called “homeopathic remedies” really are: IONIZED PHARMACEUTICALS.

IF YOU STILL DON’T BELIEVE THIS . . 

If you don’t believe that properties of the solute remain in solvents diluted beyond the putative limit . . make the assays for ionic concentration, i.e. do the tests to identify homeopathic remedies from plain water!

PUT IT TO THE TEST! (James Randi, get your wallet out)

Test question: What are the assays for ionized pharmaceuticals?

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